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070300|化学专业硕士研究生指导教师ClickNum:360
姓名 刘勇 性别
民族汉族出生年月1986-1
学历|学位研究生|博士专业技术职务 讲师
行政职务
联系电话0531-82769131移动电话13969043881
邮箱lycc2010@126.com
通讯地址 | 邮编山东济南市南辛庄西路336号 | 250022
招生方向(领域) 02(全日制)分析化学,03(全日制)有机化学
研究领域、学习工作经历、学术兼职等情况

研究方向

1. 有机功能材料的设计、合成及生物成像应用

2. 荧光探针的构建及其生物分析

学习及工作经历

刘勇,男,博士,讲师,硕士研究生导师。2008年毕业于西安文理学院获学士学位,2011年毕业于西北师范大学获理学硕士学位,2014年毕业于山东大学晶体材料研究所获材料学博士学位, 2014年-至今济南大学讲师。

 

 
代表性科研成果及奖励:
(包括项目、鉴定、论文、专著、专利等)

科研论文

1.     Yong Liu,  Fangfang Meng,  Jing Nie,  Jie Niu,  Xiaoqiang Yu  and Weiying Lin . Two-photon fluorescent probe for detecting cell membranal liquid-ordered phase by an aggregate fluorescence method, J. Mater. Chem. B, 2017, 5, 4725-4731. (IF=4.57).

2.   Yong Liu, Jie Niu , Weishan Wang , Baoli Dong and Weiying Lin. Unique phenanthrenequinone imidazole-based fluorescent materials with aggregation-induced or two-photon emission. J.  Mater. Chem. B, 2017, DOI: 10.1039/C7TB02148H. (封面文章)

3.   Yong Liu, Jing Nie,  Jie Niu, Fangfang and Weiying Lin . Ratiometric fluorescent probe with AIE property for monitoring endogenous hydrogen peroxide in macrophages and cancer cells, Scientific Reports, 2017, DOI:10.1038/s41598-017-07465-5. (IF=4.55).

4.     Yong Liu,  Jie Niu, Jing Nie, Fangfang Meng and Weiying Lin. A mitochondria-targetable fluorescent probe with a large Stokes shift for detecting hydrogen peroxide in aqueous solution and living cells. New. J.Chem., 2017, 41, 3320-3325. (IF=3.2).

5.    Minggang Tian, Yong Liu (Co-first author), Yuming Sun, Ruoyao Zhang, Ruiqing Feng, et al. A single fluorescent probe enables clearly discriminating and simultaneously imaging liquid-ordered and liquid-disordered microdomains in plasma membrane of living cells. Biomaterials, 2017, 120, 46-56.  (IF=8.4)

6.   Yong Liu, Fangfang Meng, Longwei He, Xiaoqiang Yu and Weiying Lin*Fluorescence behavior of a unique two-photon fluorescent probe in aggregate and solution states and highly sensitive detection of RNA in water solution and living systems, Chem. Commun., 2016, 52, 8838-8841.(IF=6.57).

7.     Yong Liu, Fangfang Meng, Longwei He, Keyin Liu and Weiying Lin*, A dual-site two-photon fluorescent probe for visualizing lysosomes and tracking lysosomal hydrogen sulfide with two different sets of fluorescence signals in the living cells and mouse liver tissues, Chem. Commun., 2016, 52, 7016-7019.(IF=6.57)

8.      Yong Liu, Fangfang Meng and Weiying Lin*, Single fluorescent probe for reversibly detecting copper ions and cysteine in a pure water system, RSC Adv., 2016, 6, 30951–30955.(IF=3.3).

9.      Yong Liu, Fangfang Meng, Yonghe Tang, Xiaoqiang Yu and Weiying Lin*, A photostable fluorescent probe for rapid monitoring and tracking of a trans-membrane process and mitochondrial fission and fusion dynamics, New J. Chem., 2016, 40, 3726—3731. (IF=3.2).

10.   Yong Liu, Weijia Zhang, Yuming Sun, Guofen Song, Fang Miao and Xiaoqiang Yu*, Two-photon fluorescence imaging of RNA in nucleoli and cytoplasm in living cells based on low molecular weight probes, Dyes and Pigments, 2014, 103, 191-201. (IF=4.0).

11.    Fangfang Meng (指导研究生), Yong Liu, Jie Niu and Weiying Lin, Novel alkyl chain-based fluorescent probes with large Stokes shifts used for  imaging the cell membrane and mitochondria in different living cell lines. RSC Advances, 2017, 7 (26) :16087-16091.

12.   Fangfang Meng (指导研究生), Yong Liu, Yonghe Tang, Xiaoqiang Yu and Weiying Lin, A dual-site two-photon fluorescent probe for visualizing mitochondrial aminothiols in living cells and mouse liver tissues, New J. Chem., 2016, 40, 7399-7406.

13.    Wenchao DingYong LiuYijing LiQiurong Shi, Houshen LiHaibing Xia*Dayang WangXutang TaoWater-soluble Gold Nanoclusters with pH-dependent Fluorescence and High Colloidal Stability over a Wide pH Range via Co-reduction of Glutathione and Citrate. RSC Advances2014, 4, 22651-22659.

14.     Guofen Song, Yuming Sun, Yong Liu, Xiankun Wang, Meiling Chen, Fang Miao, Weijia Zhang, Xiaoqiang Yu*, Jianling Jin, Low molecular weight fluorescent probes with good photostability for imaging RNA-rich nucleolus and RNA in cytoplasm in living cells. Biomaterials, 2014, 35, 2103-2112.

15.    Baoli Dong, Xuezhen Song, Xiuqi Kong, Chao Wang, Yonghe Tang, Yong Liu and Weiying Lin*, Adv. Mater. 2016, DOI: 10.1002/adma.201602939

16.    Junjie WangYuming SunWeijia ZhangYong LiuXiaoqiang Yu*Ning Zhao, A two-photon ratiometric fluorescent probe enables spatial coordinates determination of intracellular pH. Talanta2014, 129, 241-248.

17.   Zhiguang Yang, Ning Zhao, Yuming Sun, Fang Miao, Yong Liu, Xin Liu, Yuanhong Zhang, Wentao Ai, Guofen Song, Xiaoyuan Shen, Xiaoqiang Yu*, Jingzhi Sun, Wai-Yeung Wong, Highly selective red- and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells. Chem. Commun., 2012, 48, 3442–3444.

18.   Fang Miao, Weijia Zhang, Yuming Sun, Ruoyao Zhang, Yong Liu, Fuqiang Guo, Guofen Song, Minggang Tian, Xiaoqiang Yu*, Novel fluorescent probes for highly selective two-photon imaging of mitochondria in living cells, Biosens.Bioelectron., 2014, 55, 423-429.

19.   Fang Miao, Weijia Zhang,Yuming Sun, Ruoyao Zhang, Yong Liu, Fuqiang Guo, Guofen Song, Minggang Tian, Xiaoqiang Yu*, High selectively fluorescence imaging of intracellular acidic compartments with a new one-photon ratiometric and two-photon turn-on acidic pH probe,  Biosens.Bioelectron., 2013, 50, 42-49.



 

承担项目

国家青年基金

项目名称:基于新型近红外荧光探针追踪癌细胞内核糖核酸(RNA)附近过氧化氢的动态变化研究;项目编号:51503077,经费:23.9万元,完成年限:201601 201812月;项目负责人:刘勇。

山东省培养基金

项目名称:构建新型近红外荧光探针追踪癌细胞内线粒体附近过氧化氢动态变化的研究;项目编号:ZR2015PE001; 经费:6万元,完成年限:20157 201612; 项目负责人:刘勇。(已经结题)

济南大学博士基金

项目名称:基于咔唑类双光子荧光探针的设计、合成及其对膜有序相的检测,项目编号:160082102,经费:5万元,完成年限:20157 201612; 项目负责人:刘勇。(已经结题)

 

发明专利

(1)     林伟英,刘勇,孟芳芳,石起慢,一种水相中专一识别二价铜离子的荧光探针及应用

(申请号:201510204193.7)已授权。

2)林伟英,刘勇,孟芳芳,石起慢,一种识别溶酶体内硫化氢的荧光探针的合成及应用

(申请号:201510305957.1)已授权

(3) 林伟英,刘勇,孟芳芳,一种识别线粒体pH的双光子荧光探针及应用

(申请号:201610801435.5

(4)     林伟英,孟芳芳,刘勇,一种具有AIE特征并连续识别钯离子、CO的荧光探针及应用

(申请号:201610801733.4

 

 

 

 

 

教学及研究生培养情况

 

本科生教学

2015年,《物理化学》助教(化工学院应用化学类本科生);

《物理化学实验》助教(化工学院化学类本科生)

2016年承担《化学制药与工艺学》和《化工原理》两门课程(生物学院制药类本科生)

 

【学生培养

本科生培养:指导本科生李胜鹏本科毕业论文获得优秀本科生毕业论文。

                     指导本科生获创新实验第三名。

研究生培养: 现指导两名研究生进行科学研究。顺利毕业一名。

 

 
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